Posted in Breast Stories | By Yasmin S.

Pueraria mirifica is a Thai herb rich in phytoestrogens, plant compounds that mimic estrogen activity in the body.
Similarity to Synthetic Estrogen
Studies show that phytoestrogens in Pueraria mirifica have effects similar to 17-alpha-ethinylestradiol, a synthetic estrogen used in hormone replacement therapy (HRT) for menopausal women.
Benefits for Menopausal Women
Research found that Pueraria mirifica helps relieve symptoms caused by low estrogen, including:
- Hot flashes
- Anxiety and restlessness
- Insomnia
- Dry skin
It also helps maintain bone mass, reducing the risk of osteoporosis in postmenopausal women.
Effect on Menstrual Cycle and Hormones
In animal studies:
- 10 and 100 mg/kg/day: Lengthened menstrual cycles
- 1000 mg/kg/day: Stopped ovulation completely
This indicates that very high doses can affect hormone levels and fertility.
Safety and Toxicity
Studies found that:
- Pueraria mirifica did not cause toxicity or organ damage at doses of 10 and 100 mg/kg/day.
- No skin or eye irritation was reported.
However, further molecular studies are needed to confirm its safety and efficacy in humans.
Recommended Dosage
For human use, the safe dose is:
- 1-2 mg/kg/day, or
- Approximately 50-100 mg per day
This dose is considered safe for overall body systems.
Conclusion
Pueraria mirifica’s phytoestrogens provide estrogen-like benefits similar to synthetic hormones such as 17-alpha-ethinylestradiol. It offers a natural option for easing menopausal symptoms, but appropriate dosage and further studies are important for long-term safety.
Reference:
Pueraria mirifica: Queen of Thai Herb (PDF)